Windy City Media Group Frontpage News
Celebrating 30 Years of Gay Lesbian Bisexual and Trans News
home search facebook twitter join
Gay News Sponsor Windy City Times 2017-07-26
DOWNLOAD ISSUE
About WCMG Publications News Index  Entertainment Features Bars & Clubs Calendar Videos Advertisers OUT! Guide    Marriage

Sponsor
Sponsor
Sponsor

  WINDY CITY TIMES

Stem-cell transplants working in two HIV patients
From an amfAR press release
2013-07-03

facebook twitter google +1 reddit email


NEW YORK, July 3, 2013 — Dr. Timothy Henrich of Harvard Medical School and Brigham and Women's Hospital in Boston today reported on the case of two HIV-positive patients who show no trace of virus following stem-cell transplants. The findings were presented at the International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention in Kuala Lumpur, Malaysia.

The patients had been on long-term antiretroviral therapy for HIV when they developed lymphoma. To treat the cancer, the patients underwent reduced intensity chemotherapy followed by stem-cell transplants. Since the transplants, Dr. Henrich has been unable to find any evidence of HIV infection.

Dr. Henrich was awarded a grant through the amfAR Research Consortium on HIV Eradication (ARCHE) after presenting preliminary findings on these patients at the International AIDS Conference last July. With support from amfAR, he conducted a clinical study in which his research team withdrew the patients' antiretroviral therapy and performed several sophisticated assays looking for signs of viral rebound in blood and other tissues. One patient has been off treatment with no detectable virus for approximately 15 weeks, and the second patient for seven weeks, with similar results. However, it is too soon to draw any definitive long-term conclusions.

It is also unclear how long viral rebound might take in a patient whose viral reservoirs have been dramatically depleted, but not eradicated. According to amfAR/ARCHE grantee Dr.Robert Siciliano of Johns Hopkins University, it may take over a year. Previously a patient in a study by the National Institutes of Health had gone 50 days after treatment withdrawal without viral rebound. Dr. Henrich's patients are at or beyond this threshold, and more definitive answers will emerge as these patients continue to be closely monitored.

"These findings clearly provide important new information that might well alter the current thinking about HIV and gene therapy," said amfAR CEO Kevin Robert Frost. "While stem-cell transplantation is not a viable option for people with HIV on a broad scale because of its costs and complexity, these new cases could lead us to new approaches to treating, and ultimately even eradicating, HIV."

The first person to be cured of HIV, Timothy Brown ("the Berlin patient"), also underwent a stem-cell transplant to treat his leukemia. These new cases differ significantly, however, in that the stem-cell donors lacked the genetic mutation (CCR5 delta32) that renders a person virtually resistant to HIV infection. Nor did Dr. Henrich's patients undergo the intensive chemotherapy or total body irradiation that preceded Timothy Brown's stem-cell transplant.

"Dr. Henrich is charting new territory in HIV eradication research," said amfAR Vice President and Director of Research Dr. Rowena Johnston. "Whatever the outcome, we will have learned more about what it will take to cure HIV. We believe amfAR's continued investments in HIV cure-based research are beginning to show real results and will ultimately lead us to a cure in our lifetime."


facebook twitter google +1 reddit email




Windy City Media Group does not approve or necessarily agree with the views posted below.
Please do not post letters to the editor here. Please also be civil in your dialogue.
If you need to be mean, just know that the longer you stay on this page, the more you help us.


  ARTICLES YOU MIGHT LIKE

Gay News

GUEST COLUMN Black and Pink comes to Chicago 2017-07-26 - This August, Chicago is poised to make queer history. From August 4-6, the Windy City will host one of the largest gatherings of ...


Gay News

Black and Pink to hold family gathering in Chicago 2017-07-26 - Black and Pink will hold its second-ever family gathering in Chicago on Aug. 4-6. The gathering will bring together formerly incarcerated LGBTQ and/or ...


Gay News

Windy City Times Job Fair Sept. 22 at Center on Halsted 2017-07-26 - More than 70 major corporations, small businesses, government agencies and nonprofits are expected for the third annual in the Windy City Times WERQ! ...


Gay News

Leadership program for LGBTQ youth, HIV/AIDS-affected youth begins in Vietnam 2017-07-25 - Hanoi, 19 July 2017 — Amazin LeThi Foundation today, announced the launch of the Leadership Sports and Education Program, co-implemented by the Community-based ...


Gay News

Equality Illinois, AIDS Foundation of Chicago to blend beach party with civic engagement 2017-07-25 - CHICAGO—Equality Illinois and AIDS Foundation of Chicago are excited to announce Fahrenheit Chicago—Pride South on the Lake, an end-of-summer beach party of fun, ...


Gay News

Hundreds tackle 200-mile Ride For AIDS Chicago 2017-07-11 - Kelly Southard was in her fourth Ride For AIDS Chicago—the two-day, 200-mile bicycle ride July 8-9, organized and benefitting the Test Positive Aware ...


Gay News

Walgreens clinics in select markets to begin PrEP prescriptions 2017-07-10 - Deerfield-based Walgreens announced on July 10 that providers at Walgreens Healthcare Clinics in select markets would soon be able to provide patients with ...


Gay News

AIDSVu maps show disproportionate HIV burden among youth, communities of color 2017-07-05 - ATLANTA, Today, AIDSVu released new interactive maps illustrating the impact of HIV across the United States, showing that two-thirds of all new HIV ...


Gay News

Former member of Pres. Advisory Council on HIV/AIDS on White House HIV remarks 2017-06-28 - ( Chicago, IL, June 27, 2017 )—Today, President Trump issued a statement to mark National HIV Testing Day. This is the first statement ...


Gay News

UIC launches injectable PrEP study 2017-06-21 - The University of Illinois at Chicago ( UIC ), on June 16, announced that it will begin recruiting participants for a clinical trial ...


 



Copyright © 2017 Windy City Media Group. All rights reserved.
Reprint by permission only. PDFs for back issues are downloadable from
our online archives. Single copies of back issues in print form are
available for $4 per issue, older than one month for $6 if available,
by check to the mailing address listed below.

Return postage must accompany all manuscripts, drawings, and
photographs submitted if they are to be returned, and no
responsibility may be assumed for unsolicited materials.
All rights to letters, art and photos sent to Nightspots
(Chicago GLBT Nightlife News) and Windy City Times (a Chicago
Gay and Lesbian News and Feature Publication) will be treated
as unconditionally assigned for publication purposes and as such,
subject to editing and comment. The opinions expressed by the
columnists, cartoonists, letter writers, and commentators are
their own and do not necessarily reflect the position of Nightspots
(Chicago GLBT Nightlife News) and Windy City Times (a Chicago Gay,
Lesbian, Bisexual and Transegender News and Feature Publication).

The appearance of a name, image or photo of a person or group in
Nightspots (Chicago GLBT Nightlife News) and Windy City Times
(a Chicago Gay, Lesbian, Bisexual and Transgender News and Feature
Publication) does not indicate the sexual orientation of such
individuals or groups. While we encourage readers to support the
advertisers who make this newspaper possible, Nightspots (Chicago
GLBT Nightlife News) and Windy City Times (a Chicago Gay, Lesbian
News and Feature Publication) cannot accept responsibility for
any advertising claims or promotions.

 

 

 

TRENDINGBREAKINGPHOTOS

Sponsor
Sponsor


 



Sponsor

About WCMG Publications News Index  Entertainment Features Bars & Clubs Calendar Videos Advertisers OUT! Guide    Marriage


About WCMG      Contact Us      Online Front  Page      Windy City  Times      Nightspots      OUT! Guide     
Identity      BLACKlines      En La Vida      Archives      Subscriptions      Distribution      Windy City Queercast     
Queercast Archives      Advertising  Rates      Deadlines      Advanced Search     
Press  Releases      Event Photos      Join WCMG  Email List      Email Blast     
Upcoming Events      Todays Events      Ongoing Events      Post an Event      Bar Guide      Community Groups      In Memoriam      Outguide Categories      Outguide Advertisers      Search Outguide      Travel      Dining Out      Blogs      Spotlight  Video     
Classifieds      Real Estate      Place a  Classified     

Windy City Media Group produces Windy City Queercast, & publishes Windy City Times,
The Weekly Voice of the Gay, Lesbian, Bisexual and Trans Community,
Nightspots, Out! Resource Guide, and Identity.
5315 N. Clark St. #192, Chicago, IL 60640-2113 • PH (773) 871-7610 • FAX (773) 871-7609.