Windy City Media Group Frontpage News Home
CELEBRATING 28+ YEARS OF Lesbian Gay Bisexual and Transgender NEWS

Search Gay News Articles
Advanced Search
Gay News Sponsor Windy City Times 2014-10-29
Download Issue
  News Index       Archives   About WCMG    Publications    Bars & Clubs     Calendar   Videos   Advertisers    OUT! Guide    Classifieds   AIDS @ 32
 Local | National | World | Politics | Obits | Profiles | Views | Entertainment | Theater | Dance | Music | Film | Art | Books | TV/Gossip
 Travel | History | Marriage | Youth | Trans | Lesbian | Celebrations | Food | Nightlife | Sports | Health | Real Estate | Autos | Pets | Crime

Sponsor
Knight at the Movies: Olive Kitteridge; To Russia with Love Knight at the Movies: Olive Kitteridge;
To Russia
with Love
With his star turn in Birdman, Michael Keaton is deservedly this year's ...

Browse Gay News Index   Browse Gay News Archives
  Windy City Times    Download PDF Issue

Stem-cell transplants working in two HIV patients
From an amfAR press release
2013-07-03

facebook twitter del.icio.us stumble upon digg google +1 reddit email


NEW YORK, July 3, 2013 — Dr. Timothy Henrich of Harvard Medical School and Brigham and Women's Hospital in Boston today reported on the case of two HIV-positive patients who show no trace of virus following stem-cell transplants. The findings were presented at the International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention in Kuala Lumpur, Malaysia.

The patients had been on long-term antiretroviral therapy for HIV when they developed lymphoma. To treat the cancer, the patients underwent reduced intensity chemotherapy followed by stem-cell transplants. Since the transplants, Dr. Henrich has been unable to find any evidence of HIV infection.

Dr. Henrich was awarded a grant through the amfAR Research Consortium on HIV Eradication (ARCHE) after presenting preliminary findings on these patients at the International AIDS Conference last July. With support from amfAR, he conducted a clinical study in which his research team withdrew the patients' antiretroviral therapy and performed several sophisticated assays looking for signs of viral rebound in blood and other tissues. One patient has been off treatment with no detectable virus for approximately 15 weeks, and the second patient for seven weeks, with similar results. However, it is too soon to draw any definitive long-term conclusions.

It is also unclear how long viral rebound might take in a patient whose viral reservoirs have been dramatically depleted, but not eradicated. According to amfAR/ARCHE grantee Dr.Robert Siciliano of Johns Hopkins University, it may take over a year. Previously a patient in a study by the National Institutes of Health had gone 50 days after treatment withdrawal without viral rebound. Dr. Henrich's patients are at or beyond this threshold, and more definitive answers will emerge as these patients continue to be closely monitored.

"These findings clearly provide important new information that might well alter the current thinking about HIV and gene therapy," said amfAR CEO Kevin Robert Frost. "While stem-cell transplantation is not a viable option for people with HIV on a broad scale because of its costs and complexity, these new cases could lead us to new approaches to treating, and ultimately even eradicating, HIV."

The first person to be cured of HIV, Timothy Brown ("the Berlin patient"), also underwent a stem-cell transplant to treat his leukemia. These new cases differ significantly, however, in that the stem-cell donors lacked the genetic mutation (CCR5 delta32) that renders a person virtually resistant to HIV infection. Nor did Dr. Henrich's patients undergo the intensive chemotherapy or total body irradiation that preceded Timothy Brown's stem-cell transplant.

"Dr. Henrich is charting new territory in HIV eradication research," said amfAR Vice President and Director of Research Dr. Rowena Johnston. "Whatever the outcome, we will have learned more about what it will take to cure HIV. We believe amfAR's continued investments in HIV cure-based research are beginning to show real results and will ultimately lead us to a cure in our lifetime."


facebook twitter del.icio.us stumble upon digg google +1 reddit email




Windy City Media Group does not approve or necessarily
agree with the views posted below.
Please do not post letters to the editor here.
Please also be civil in your dialogue.
If you need to be mean, just know that the longer you
stay on this page, the more you help us.

French PrEP study suggests "on-demand" dosages may be effective 2014-10-30
Barlesque Strip-a-Thon benefits TPAN throughout November 2014-10-28
Chicago man accused of criminal HIV transmission 2014-10-26
Cuomo's AIDS task force; 'drag queen' comment; Jazz Jennings 2014-10-21
White House addressing intersection of HIV/AIDS, violence with women, girls 2014-10-21
AFC ad urges Mexican men to get tested 2014-10-15
HRC scores 113th Congress; Alaska marries; WH looks at AIDS, violence 2014-10-13
AIDS Foundation of Chicago's 30th annual AIDS Run/Walk. 2014-10-01
Gay/bi men see HIV as top health issue facing community 2014-09-27
CDC: Half gay/bi men diagnosed with HIV get treatment 2014-09-26
AIDS Foundation of Chicago names John Peller President/CEO 2014-09-25
AIDS activist Staley on being a baby boomer, HIV treatments 2014-09-18
Coalition continues push for rescinded HIV/AIDS allocations 2014-09-17
Proud to Run opens applications for 2015 beneficiaries 2014-09-17
Nat'l HIV/AIDS, Aging Awareness Day; Richmond, Va.'s, pitch 2014-09-16
Thousands run, walk to fight HIV/AIDS 2014-09-14
Agencies push state to release HIV/AIDS funds 2014-09-10
Women's Film; Martina proposes; Sky finals; AIDS Run, Walk 2014-09-09
TPAN launches 2014's 'A Day with HIV' 2014-09-08
Agencies push state to release HIV/AIDS funds 2014-09-07
SPORTS EVENTS AIDS Run; Race Judicata, tennis tournament 2014-09-03
HBHC responds to AHF anti-PrEP ads 2014-08-30
Lambda launches Know Your Rights At Work for LGBT, HIV+ 2014-08-27
Attendees board 'Soul Train' at ALCC event 2014-08-27
World AIDS Museum opens in Fort Lauderdale 2014-08-26
A Day with HIV, Chicago Cultural Center, Sept. 5 2014-08-24
NLGJA 2014: Health writers discuss HIV/AIDS reporting 2014-08-24
Red Pump Project talks HIV/AIDS awareness 2014-08-20
DANCE Francisco AviƱa's one-man show is about 'A.r.T.' 2014-08-19
AFC in report to UN about HIV and minorities 2014-08-13
Federal officials discuss HIV/AIDS progress 2014-08-10
HIV/AIDS, stigma fight brings lesbian couple together 2014-08-06
Mother of Ryan White to Congress: Maintain commitment 2014-07-30
Ryan White's mom's campaign; HIV removed from human cells 2014-07-30
AIDS policy listening session Aug. 5 2014-07-30
SAID tags +$500M toward creating AIDS-free generation 2014-07-27
Lambda: Stop HIV-based prosecutions due to DOJ guidance 2014-07-27
CDPH launches Project CHAT 2014 survey to inform HIV plans 2014-07-27
PrEP effective with few doses a week; no new dosing strategies 2014-07-23
Journalist Vargas detained; Lambda Legal's call 2014-07-22





Copyright © 2014 Windy City Media Group. All rights reserved.
Reprint by permission only. PDFs for back issues are downloadable from
our online archives. Single copies of back issues in print form are
available for $4 per issue, older than one month for $6 if available,
by check to the mailing address listed below.

Return postage must accompany all manuscripts, drawings, and
photographs submitted if they are to be returned, and no
responsibility may be assumed for unsolicited materials.
All rights to letters, art and photos sent to Nightspots
(Chicago GLBT Nightlife News) and Windy City Times (a Chicago
Gay and Lesbian News and Feature Publication) will be treated
as unconditionally assigned for publication purposes and as such,
subject to editing and comment. The opinions expressed by the
columnists, cartoonists, letter writers, and commentators are
their own and do not necessarily reflect the position of Nightspots
(Chicago GLBT Nightlife News) and Windy City Times (a Chicago Gay,
Lesbian, Bisexual and Transegender News and Feature Publication).

The appearance of a name, image or photo of a person or group in
Nightspots (Chicago GLBT Nightlife News) and Windy City Times
(a Chicago Gay, Lesbian, Bisexual and Transgender News and Feature
Publication) does not indicate the sexual orientation of such
individuals or groups. While we encourage readers to support the
advertisers who make this newspaper possible, Nightspots (Chicago
GLBT Nightlife News) and Windy City Times (a Chicago Gay, Lesbian
News and Feature Publication) cannot accept responsibility for
any advertising claims or promotions.

 

 

 

Sponsor
Sponsor
Sponsor
Sponsor


 

PASSAGES Former Chicagoan Steven Moore dies
 
Strict ID laws could hinder trans voters
 
Neil Patrick news; 'Freeheld' has problem; 'Divas Simply Singing'
 
Music, radio are David Polk's passion, profession
 
Egalite Chicago forum on LGBT activism post marriage equality
 
Windy City Times Current DownloadNightspots Current DownloadQueercast Current Download
Windy City Media Group BlogsJoin Our Email List!Donate Now
Sponsor


Sponsor

  News Index       Archives   About WCMG    Publications    Bars & Clubs     Calendar   Videos   Advertisers    OUT! Guide    Classifieds   AIDS @ 32
 Local | National | World | Politics | Obits | Profiles | Views | Entertainment | Theater | Dance | Music | Film | Art | Books | TV/Gossip
 Travel | History | Marriage | Youth | Trans | Lesbian | Celebrations | Food | Nightlife | Sports | Health | Real Estate | Autos | Pets | Crime



About WCMG      Contact Us      Online Front  Page      Windy City  Times      Nightspots      OUT! Guide     
Identity      BLACKlines      En La Vida      Archives      Subscriptions      Distribution      Windy City Queercast     
Queercast Archives      Advertising  Rates      Deadlines      Advanced Search     
Press  Releases      Event Photos      Join WCMG  Email List      Email Blast     
Upcoming Events      Todays Events      Ongoing Events      Post an Event      Bar Guide      Community Groups      In Memoriam      Outguide Categories      Outguide Advertisers      Search Outguide      Travel      Dining Out      Blogs      Spotlight  Video      News Videos      Nightspots Videos      Entertainment Videos      Queercast Videos      Comedy Videos     
Classifieds      Real Estate      Place a  Classified     

Windy City Media Group produces Windy City Queercast, & publishes Windy City Times,
The Weekly Voice of the Gay, Lesbian, Bisexual and Trans Community,
Nightspots, Out! Resource Guide, and Identity.
5315 N. Clark St. #192, Chicago, IL 60640-2113 • PH (773) 871-7610 • FAX (773) 871-7609.